Original / Pocket · Collector guide
Dr. Mario
Game Boy · 1990 · Rank #6
A portable Nintendo puzzle spin-off built around colored capsules and virus-clearing matches.

- Release year
- 1990
- Top-10 rank
- #6
- Reported sales
- 5,340,000
Game notes
What it is & why collectors want it
- The Game Boy version is a 1990 falling-capsule puzzle game: match colors to clear the viruses on screen.History source ↗
- The title became a lasting Nintendo puzzle series, with later ports and remakes across home and handheld systems.History source ↗
- Collector angle: the Game Boy release preserves the compact early handheld take on Nintendo’s puzzle format.History source ↗
Before you buy
What to look for
- Loose cartridge: a lower-cost way to collect; ask for clear front, back, and connector photos, plus a working/test or return policy.
- Complete in box: verify box, manual, and inserts are actually included and match the game’s version and region; check condition in separate photos.
- Sealed: request clear photos of all sides and the wrap. Shrink wrap by itself is not proof of a factory seal.
- Authenticity clues: compare label color and print, spelling, the stamped two-digit label code, Nintendo / “Made in Japan” back markings, and the correct 3.8 mm Game Boy screw. These are clues, not proof; an opened-cart board should be compared with a known-good copy of the same game and region.
Visual signs are not definitive authentication. Ask for specific photos and compare against trusted references; for uncertain or high-value carts, consider an in-person board inspection.
Cartridge authentication guidance: Epilogue’s Game Boy inspection guide ↗
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